She is on
trial for larceny.
她是因窃盗罪受审。
The new drug is still in the clinical
trial process.
这种新药还在进行临床试验。
This game is a
trial of strength.
这场比赛是一场实力的较量。
A 1000-kilowatt alternating current transmission project from Zhumadian in Henan province to Wuhan in Hubei province successfully concluded its 72-hour trial run and smoothly entered full operation on Sunday, enhancing stable winter power supply for the two provinces.
周日，河南驻马店至湖北武汉的1000千瓦交流输电工程顺利完成72小时试运行，顺利进入全面运行，增强了两省冬季稳定电力供应。
During the CIIE, Boehringer Ingelheim also exhibited a new drug candidate at the Phase-3 clinical trial for treating idiopathic pulmonary fibrosis, a rare and chronic lung disease.
在CIIE期间，勃林格殷格翰还在治疗特发性肺纤维化（一种罕见的慢性肺病）的3期临床试验中展示了一种新的候选药物。
A multi-center, double-blind clinical trial showed an average of 59 percent reduction in myopia progression when full-time wearing the lenses, including near activities, for 24 months.
一项多中心双盲临床试验显示，全时佩戴隐形眼镜（包括近距离活动）24个月后，近视进展平均减少59%。
Meanwhile, the company can introduce drugs and medical devices used in Hong Kong and Macao public hospitals for urgent clinical use to certain hospitals in Guangdong province on a trial basis.
同时，该公司可以将香港和澳门公立医院用于紧急临床的药物和医疗器械试点引入广东省的某些医院。
The Shell Recharge Shenzhen Airport EV Station served more than 3,300 EVs every day during its trial operation.
壳牌充电深圳机场电动汽车站试运营期间，每天为3300多辆电动汽车提供服务。
The company said it is looking for partnerships with companies and medical institutions to improve AI doctors' accuracy, train them to diagnose more diseases and will run a bigger trial later this year.
该公司表示，正在寻求与公司和医疗机构建立合作伙伴关系，以提高人工智能医生的准确性，培训他们诊断更多疾病，并将在今年晚些时候进行更大规模的试验。
Adora Magic City, China's first domestically made large cruise ship, completed its first trial voyage on Monday, one day ahead of its schedule, according to China State Shipbuilding Corp (CSSC) Shanghai Waigaoqiao Shipbuilding Co Ltd. During the eight-day trial voyage, which involved 1,217 people, the 135,500-gross-tonnage vessel completed tests of key systems, equipment performance and two critical technologies.
据中国船舶重工股份有限公司（CSSC）上海外高桥造船有限公司介绍，中国第一艘国产大型邮轮“阿多拉魔城”于周一完成了首次试航，比原定计划提前了一天，设备性能和两项关键技术。
Currently, the trial operation of Suzhou Rail Transit Line 11 is drawing to a close.
目前，苏州市轨道交通11号线试运营已接近尾声。
It is expected that a trial operation with passengers will be carried out in the middle of this year.
预计将于今年年中进行载客试运行。
"During the project's trial run, the CCUS system demonstrated reliable performance and high safety standards, and the energy efficiency indicators and product quality are at or above their designed levels," said Ji Mingbin, president of China Energy's Jiangsu branch.
中国能源江苏分公司总裁纪明斌表示：“在项目试运行期间，CCUS系统表现出可靠的性能和高安全标准，能效指标和产品质量均达到或高于设计水平。”。
The Hong Kong liquefied natural gas or LNG project, whose trial operations started on Sunday, is expected to significantly optimize the energy structure of the Guangdong-Hong Kong-Macao Greater Bay Area while ensuring domestic energy security, industry experts said on Monday.
行业专家周一表示，香港液化天然气或液化天然气项目将于周日开始试运行，预计该项目将在确保国内能源安全的同时，显著优化广东-香港-马槽大湾区的能源结构。
The Hong Kong liquefied natural gas (LNG) project entered into trial operation on Sunday and is expected to significantly increase the proportion of clean energy generation in Hong Kong Special Administrative Region while optimizing the energy structure of the Guangdong-Hong Kong-Macao Greater Bay Area, said its operator China Offshore Oil Engineering Co Ltd. As the largest offshore energy infrastructure construction project in recent years in Hong Kong, the Hong Kong LNG project includes a dual-berth offshore LNG receiving terminal, an onshore LNG receiving terminal and two submarine pipelines, according to the company, a listed company controlled by China National Offshore Oil Corporation.
香港液化天然气项目于周日开始试运行，其运营商中国海洋石油工程有限公司表示，该项目有望大幅提高香港特别行政区清洁能源发电的比例，同时优化广东-香港-马考大湾区的能源结构。中国海洋石油总公司控股的上市公司香港液化天然气项目是香港近年来最大的海上能源基础设施建设项目，包括一个双泊位海上液化天然气接收站、一个陆上液化天然气接收站和两条海底管道。
Cando Drones, an Israeli aviation company participating in the test flights, said the drones are expected to conduct trial flights in June once the aviation permits are received.
参与试飞的以色列航空公司Cando Drones表示，一旦获得航空许可，这些无人机预计将于6月进行试飞。
The two parties will trial pilot-scale demonstrations of carbon capture and utilization technologies at HBIS' steel operations in China to develop and test technologies that can be integrated into steel production processes to reduce carbon emissions.
双方将在河钢在中国的钢铁业务中试行碳捕获和利用技术的中试示范，以开发和测试可集成到钢铁生产过程中以减少碳排放的技术。
The two parties will trial pilot-scale demonstrations of carbon capture and utilization technologies at HBIS' steel operations in China as part of this new project.
作为这一新项目的一部分，双方将在河钢在中国的钢铁业务中试行碳捕获和利用技术的中试示范。
The trial will develop and test technologies that can be integrated into steel production processes to reduce the CO2 emissions, it said.
该试验将开发和测试可以集成到钢铁生产过程中以减少二氧化碳排放的技术。
Unit 3 of the Fangchenggang nuclear power plant in China's Guangxi Zhuang autonomous region, the first Hualong One nuclear unit serving western China, went into operation on Saturday, 168 hours after trial operation, said its operator China General Nuclear Power Corp. Hualong One is China's third-generation nuclear power technology with full intellectual property rights.
中国广西壮族自治区防城港核电站第三单元是服务于中国西部的第一台华龙一号核机组，其运营商中国通用核电有限公司表示，该机组在试运行168小时后于周六投入运行。
Everest said the base launched trial production in December and has proven capable of large-scale production of mRNA vaccines.
Everest表示，该基地于12月开始试生产，并已证明有能力大规模生产信使核糖核酸疫苗。
At China's first trial production line for quantum chips in Hefei, Anhui province, engineers at Origin Quantum, a startup founded in 2017, are busy testing products.
在安徽合肥的中国第一条量子芯片试生产线，成立于2017年的初创公司Origin quantum的工程师们正忙于测试产品。
The 27.1-kilometer Nairobi Expressway, built by a Chinese firm under a public-private partnership model, marked a milestone of 10 million total trips on Tuesday by vehicles that have driven on it since its trial operation began in May 2022.
这条全长27.1公里的内罗毕高速公路由一家中国公司按照公私合作模式建造，标志着自2022年5月试运营以来，周二行驶的车辆总出行量达到1000万次的里程碑。
"I started using the expressway when it was in the trial phase.
“我开始使用高速公路是在试验阶段。
Zhao Yang, chief executive officer of Moja Expressway Co, which manages the operation of the expressway, said that an average of 50,000 motorists are using it daily, up from 10,000 when the trial operation began.
管理高速公路运营的Moja高速公路公司首席执行官赵杨表示，平均每天有5万名驾车者使用高速公路，而试运营开始时只有1万人。
The train has completed trial runs along four subway lines in Porto and has proved that it's compatible with existing trains in the city.
该列车已在波尔图的四条地铁线路上完成试运行，并已证明与该市现有列车兼容。
China National Petroleum Corp started trial runs of its mega greenfield refinery complex in Guangdong on Sunday, said the nation's largest oil and gas producer by domestic annual output.
中国石油天然气集团公司表示，其位于广东的大型绿地炼油厂已于周日开始试运行。
The Beijing-based company launched its first generation of AI desks late last year for trial and within four months, the product made it into the top four desks sold on Alibaba's Tmall, in terms of gross merchandise volume.
这家总部位于北京的公司去年年底推出了第一代人工智能办公桌进行试用，不到四个月，该产品就进入了阿里巴巴天猫上商品总量排名前四的办公桌。
Veolia currently operates a trial recycling project for used power batteries in Jiangmen, Guangdong province.
威立雅目前在广东省江门市开展废旧动力电池回收试验项目。
Moja Expressway Company CEO Steve Zhao said in the Kenyan capital of Nairobi that the motorway has become an attractive mode of transport; between May, when it started trial run, and Dec 1, the total traffic volume of the expressway has exceeded 7.6 million vehicles.
Moja高速公路公司首席执行官Steve赵在肯尼亚首都内罗毕表示，高速公路已成为一种有吸引力的交通方式；从5月开始试运行到12月1日，高速公路的总交通量已超过760万辆。
Business has been good since it started its trial operation in late June, and it usually requires reservations two to three days in advance to book private rooms.
自6月底开始试营业以来，生意一直很好，通常需要提前两到三天预订私人房间。
The Shenmu-Anping coal bed methane pipeline, China's longest such pipeline, was put into trial operation on Thursday, which will eventually ensure sufficient domestic gas supply, said its operator China National Offshore Oil Corp.
中国海洋石油总公司表示，中国最长的煤层气管道神木-安平煤层气管道已于周四试运行，这将最终确保国内天然气供应充足。
China's longest coal bed methane pipeline, the Shenmu-Anping pipeline, was put into trial operation on Thursday, said its operator China National Offshore Oil Corp, the country's largest offshore driller.
中国最大的海上钻井公司中国海洋石油总公司表示，中国最长的煤层气管道神木-安平管道已于周四试运行。
For their part, domestic companies, particularly those from the retail sector, have adopted a trial and error approach, constantly drawing insights from consumer feedback, acting upon them to improve products, and accelerating new product launches, all to discover best-selling products.
就他们而言，国内公司，尤其是零售业的公司，采取了试错的方法，不断从消费者的反馈中汲取见解，采取行动改进产品，并加快新产品的推出，所有这些都是为了发现最畅销的产品。
A power supply project in Cambodia, involving China's largest single investment in the country, started electricity generation on Tuesday after a 72-hour trial run, its operator China Huadian Corp said on Tuesday.
柬埔寨运营商中国华电公司周二表示，柬埔寨的一个供电项目在经过72小时的试运行后于周二开始发电，该项目涉及中国在该国最大的单一投资。
"On Oct 4, Musk proposed to proceed with the deal at the original price, just ahead of a trial scheduled at the Delaware Chancery Court on Oct 17, in which Twitter was set to seek an order directing Musk to close the deal for $44 billion.
“10月4日，马斯克提议以原价继续进行这笔交易，就在定于10月17日在特拉华州衡平法院进行的审判之前，推特将寻求一项命令，指示马斯克以440亿美元的价格完成这笔交易。
In a letter sent to Twitter, Musk offered to continue the deal if the court can adjourn the trial and all other related proceedings.
在发给推特的一封信中，马斯克提出，如果法院能够推迟审判和所有其他相关诉讼，他将继续这笔交易。
A Delaware Chancery Court judge eventually ruled that Musk had until Oct 28 to cement the Twitter deal or head to trial.
特拉华州衡平法院法官最终裁定，马斯克必须在10月28日之前巩固与推特的交易，否则将接受审判。
The offer came ahead of a trial scheduled at the Delaware Chancery Court on Oct 17, in which Twitter was set to seek an order directing Musk to close the deal for $44 billion.
这一提议是在定于10月17日在特拉华州衡平法院进行审判之前提出的，推特将在审判中寻求一项命令，指示马斯克以440亿美元的价格完成这笔交易。
Twitter has sued Musk to complete the deal, and a trial is set for October.
推特已起诉马斯克以完成交易，审判定于10月进行。
The dynamic test consists of several trial runs to examine a series of key operational processes including passenger services, electrical services and the power system, said Ma Wei, an engineer on the CR24 test team.
CR24测试团队的工程师马伟说，动态测试包括几次试运行，以检查一系列关键的运营过程，包括客运服务、电力服务和电力系统。
Sinovac Biotech Ltd, a biopharmaceutical product provider in China, announced on Tuesday that a phase-3 clinical trial for its inactivated quadrivalent influenza vaccine was initiated in the Republic of Chile.
中国生物制药产品供应商科兴生物技术有限公司周二宣布，其四价流感灭活疫苗的三期临床试验已在智利共和国启动。
The clinical trial aims to evaluate the immunogenicity and safety of the quadrivalent influenza vaccine among individuals aged 3-year-old and above.
该临床试验旨在评估四价流感疫苗在3岁及以上人群中的免疫原性和安全性。
It is expected that upon acceptance and trial operations, it will be officially handed over and put into operation on Feb 28, 2025, Chen said.
陈说，预计在验收和试运行后，它将于2025年2月28日正式移交并投入运营。
Chinese vaccine producer Sinovac Biotech officially kicked off a clinical trial in Hong Kong on Monday to assess the safety and immunogenicity of its Omicron-specific COVID-19 inactivated vaccine which will be used as a booster shot in healthy adults.
中国疫苗生产商科兴生物周一在香港正式启动临床试验，以评估其奥密克戎特异性新冠肺炎灭活疫苗的安全性和免疫原性，该疫苗将用于健康成年人的加强针。
The trial program plans to recruit around 300 or more healthy volunteers who are above the age of 18 and who have already been inoculated with two or three shots of either inactivated or mRNA COVID-19 vaccine.
该试验计划招募约300名或更多18岁以上的健康志愿者，他们已经接种了两针或三针新冠肺炎灭活疫苗或mRNA疫苗。
Constructed by China Road and Bridge Corp, a subsidiary of Beijingheadquartered China Communications Construction Co Ltd, the Nairobi Expressway in Kenya, linking Jomo Kenyatta International Airport to the city's downtown district, opened for trial operations last month.
肯尼亚内罗毕高速公路由总部位于北京的中国交通建设有限公司的子公司中国路桥工程有限公司承建，连接乔莫·肯雅塔国际机场和该市市中心，于上月开通试运营。
Laekna Therapeutics, a biotechnology company in Shanghai's Zhangjiang Pharmaceutical Valley, has completed dosing the first patients in the United States and China in a phase III clinical trial for breast cancer treatment, in spite of normal operations getting disrupted by the sudden COVID flare-ups in this spring.
上海张江制药谷的生物技术公司Laekna Therapeutics在癌症治疗的三期临床试验中完成了美国和中国的首批患者的给药，尽管今年春天新冠肺炎疫情突然爆发中断了正常手术。
As such, team members had to overcome various kinds of difficulties from producing trial drugs to ensuring smooth logistics during the lockdown.
因此，团队成员必须克服各种困难，从生产试验药物到确保封锁期间的物流畅通。
"We hope to enhance cooperation with clinical research centers in Shanghai and see the acceleration of the enrollment and research process of new drug clinical trial projects of local innovative pharma companies.
“我们希望加强与上海临床研究中心的合作，并看到当地创新制药公司新药临床试验项目的注册和研究进程加快。
Indonesia, which holds the rotating Group of 20(G20) presidency in 2022, plans to launch a trial operation of a section of the line involving Tegal Luar station in the near future.
印尼是2022年20国集团轮值主席国，计划在不久的将来启动涉及Tegal Luar站的一段线路的试运营。
At present, the Chinese contractors are working hard to safeguard regular construction and ensure the trial's success and the future full operations.
目前，中国承包商正在努力保障正常施工，确保试验的成功和未来的全面运营。
The distiller started to trial its ice cream on Sunday on its official mobile app, iMaotai, with deliveries restricted to Guiyang at the moment.
周日，这家酒厂开始在其官方手机应用程序iMaotai上试用其冰淇淋，目前仅限于贵阳配送。
The World Bank's new trial standards to evaluate the satisfaction in a country's business environment for foreign companies include 10 aspects: Market access, business premise acquisition, labor employment, access to financial services, cross-border trade, tax payment, settlement of commercial disputes and promotion of market competition.
世界银行评估外国公司对一个国家商业环境满意度的新试行标准包括10个方面：市场准入、经营场所收购、劳动力就业、获得金融服务、跨境贸易、纳税、解决商业纠纷和促进市场竞争。
This same TCM is also recommended as a therapeutic drug in the notification issued by the National Health Commission on the latest Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (Trial Version 9).
在国家卫生健康委员会发布的关于新型冠状病毒肺炎最新诊疗方案（试行第九版）的通知中，也推荐该中药作为治疗药物。
It has carried out aerial tours and short-distance air traffic trial operations from nine operating points, including Guangzhou, Shenzhen, and Zhaoqing in Guangdong province, Hezhou in the Guangxi Zhuang autonomous region, Sanya in Hainan province and some other cities in cooperation with its partners.
与合作伙伴合作，在广东省广州、深圳、肇庆、广西壮族自治区贺州、海南省三亚等9个运营点开展了空中游览和短距离空中交通试运营。
Under the relevant compliance framework, the flagship two-seater passenger-grade AAV, the EHang 216, has conducted more than 4,000 trial flights for aerial sightseeing so far.
在相关合规框架下，旗舰双座客运级AAV EHang 216迄今已进行了4000多次空中观光试飞。
The functionality is in the trial phase and is "only applicable to certain markets", the company said.
该公司表示，该功能正处于试用阶段，“仅适用于某些市场”。
The ministry started the promotion of battery-swap business models for NEVs in October, and 11 cities such as Beijing, Nanjing in Jiangsu province, Wuhan in Hubei province and Hefei in Anhui province were listed among the first batch of trial cities.
10月，铁道部开始推广新能源汽车电池互换商业模式，北京、江苏南京、湖北武汉、安徽合肥等11个城市被列为首批试点城市。
The functionality is in the trial phase and is "only applicable to certain markets," company insiders confirmed with China Daily on Friday.
该公司内部人士周五向《中国日报》证实，该功能正处于试用阶段，“仅适用于某些市场”。
The ministry started the promotion of battery-swap business models for NEVs in October, with 11 cities like Beijing, Nanjing, Wuhan and Hefei being the first batch of trial cities.
铁道部于10月开始推广新能源汽车电池交换商业模式，北京、南京、武汉和合肥等11个城市成为首批试点城市。
The five-year follow-up data updates of the single-arm phase II ZUMA-1 trial showed that the five-year overall survival rate was 42.6 percent among patients that have received CAR-T cell therapy.
单臂II期ZUMA-1试验的五年随访数据更新显示，接受CAR-T细胞治疗的患者的五年总生存率为42.6%。
For lymphoma affecting the central nervous system in particular, the Department of Hematology of Tongji Hospital has led another clinical trial, specifically targeting in the long-term cure of patients in advanced stages and with CNS invasion after receiving the combined treatment of autologous hematopoietic stem-cell transplantation and CAR-T for the first time in the world.
特别是对影响中枢神经系统的淋巴瘤，同济医院血液科领导了另一项临床试验，专门针对在世界上首次接受自体造血干细胞移植和CAR-T联合治疗后，长期治愈晚期和中枢神经系统侵犯的患者。
Powered by the 5G telecommunication networks, the center relies on the EHang's command-and-control system platform to enable trial operations for the EH216, Falcon B and other eVTOL models, for various urban air mobility and smart city management applications.
该中心以5G电信网络为动力，依靠易航的指挥控制系统平台，实现EH216、Falcon B和其他eVTOL型号的试运行，用于各种城市空中交通和智能城市管理应用。
In a latest development, the company also launched a trial operation of its flagship autonomous aerial vehicle model, EH216, on Monday in Zhuhai, a coastal city in the western part of Guangdong.
最新进展是，该公司还于周一在广东西部沿海城市珠海启动了其旗舰自动驾驶飞行器型号EH216的试运行。
"For instance, we discovered in the latest trial runs that the average clientele in Suzhou is around 10 years younger than that of Shanghai," said Zhao.
赵说：“例如，我们在最近的试运行中发现，苏州的平均客户比上海年轻10岁左右。”。
By embracing artificial intelligence and advanced analytics with both structured and unstructured data, the collaboration will help provide a comprehensive picture of patients in a real-world setting, deepen the understanding of current therapies, optimize clinical trial designs, and support data-driven decision-making throughout the life cycle of drug development, the two partners said.
两位合作伙伴表示，通过将人工智能和高级分析与结构化和非结构化数据相结合，这项合作将有助于在现实世界中全面了解患者，加深对当前疗法的理解，优化临床试验设计，并支持药物开发全生命周期的数据驱动决策。
"We are looking forward to establishing a multi-layer medical security system shouldered by the government and the market economy, and promoting China's entry into more early clinical programs, as well as the mutual recognition of international clinical trial data to enable patients to use innovative medicines as early as possible," said Kang Wei, managing director of RDPAC.
RDPAC董事总经理康伟表示：“我们期待着建立一个由政府和市场经济承担的多层医疗保障体系，推动中国进入更多的早期临床项目，以及国际临床试验数据的相互认可，使患者能够尽早使用创新药物。”。
The Chinese case study presented by Zhao was a 57-year-old female, and the first patient enrolled in the pre-marketing clinical trial in China.
The McPlant will be on trial at eight restaurants in the United States — in Texas, Iowa, Louisiana and California — starting Wednesday until supplies last.
"The largest burger chain in the US believes that a limited trial will help it decide if the McPlant could fit into the existing menu.
Clover Biopharmaceuticals, a Chinese clinical-stage biopharma company developing vaccines and oncology drugs, announced on Wednesday that its protein-based COVID-19 vaccine candidate was found to be 67 percent effective against COVID-19 of any degree of severity and 79 percent against the highly infectious Delta variant in a large late-stage trial.
Efficacy of the vaccine was 92 percent against the Gamma variant and 59 percent against the Mu variant, the trial showed.
The vaccine, deploying proteins on the coronavirus to stimulate immunity against COVID-19, is also the first COVID-19 vaccine candidate in the world to demonstrate in a randomized trial significantly reduced risk of COVID-19 disease in previously infected individuals, a growing and increasingly important population as the virus continues to spread worldwide, the company claimed.
The clinical trial enrolled over 30,000 adult and elderly (≥18 years of age) participants at 31 sites in five countries (Philippines, Brazil, Colombia, South Africa, Belgium) across four continents, and is one of the most diverse COVID-19 vaccine clinical trials conducted to date.
"SPECTRA (the name of the project for the trial) enrolled participants during a time when the world encountered the rapid spread of increasingly transmissible SARS-CoV-2 variants and a takeover by Delta," said Joshua Liang, chief executive officer of Clover Biopharmaceuticals.
Sinopec, the world's largest refiner by volume, announced that as part of its efforts to step up gas storage facility construction and enhance gas storage peak-regulating capacity, its first gas storage tank in Shandong province－Shengli oilfield Yong-21 gas storage tank－began operations and started trial gas injections recently.
Some of these businesses, which have risen rapidly over the years due to the accumulation of clinical trial experience over decades, the country's streamlined medical regulatory mechanism and an ecosystem encouraging vibrant innovation under the Healthy China 2030 initiative, may even secure places in the world's first echelon of this frontier sector, the experts said.
Beijing-based YishengBio Co Ltd announced during the fair that its PIKA recombinant COVID-19 vaccine, an innovative prophylactic and therapeutic vaccine candidate against multiple SARS-CoV-2 variants, has won clinical trial approval from health authorities in the United Arab Emirates to treat patients with mild to moderate SARS-CoV-2 infections.
That marked an important milestone for the vaccine in the therapeutic arena after it received the clinical trial nod for prevention indications in the UAE and New Zealand.
"Rio Tinto said the MoU is another example of the company actively working with Chinese partners to trial and implement digital solutions, while also building on existing trade finance collaboration between Rio Tinto and Bank of China.
CNBG is currently preparing for the third-phase clinical trial on the efficacy and safety of the vaccine, which will be launched overseas, he said.
China Petrochemical Corp, or Sinopec Group, announced that its first gas storage tank in East China's Shandong province, Shengli oilfield Yong-21 gas storage tank, was put into operation and started trial gas injection on Friday.
Some of these businesses, which have risen rapidly in recent years owing to the accumulating decades of clinical trial experience, the country's streamlined medical regulatory mechanism and an ecosystem encouraging vibrant innovations under the Healthy China 2030 Initiative, may even secure places in the world's first echelon in this frontier sector, according to experts.
The three other companies agreed to a settlement, while the one from Shijiazhuang lost its first trial and lodged an appeal.
In September 2016 it won a second trial, after which the accusers appealed to the US Supreme Court for a retrial.
Finally, the appellate court abrogated the first trial, in which the Chinese companies - Hebei Welcome Pharmaceutical Co and its parent company North China Pharmaceutical Group Co - were ordered to pay $153 million to direct buyers to compensate for the "loss", according to Xinhua News Agency.
US-based Biogen Inc and Hong Kong-listed Chinese mainland biopharma startup InnoCare Pharma Ltd announced on Monday that they have entered into a license and collaboration agreement for orelabrutinib, a drug candidate currently in a multi-country, placebo-controlled Phase 2 trial for the potential treatment of multiple sclerosis, a rare disease of the nervous system characterized by loss of feeling and control of movement and speech.
Clinical trial sites set up by biotech and biopharma companies in JAPAC have increased by over 40 percent each year on average, compared to just 11 percent across the rest of the world.
The milestone payment was triggered by the inoculations of the first two patients in the Phase-1/2 clinical trial of its SHP2 inhibitor JAB-3312 in combination with PD-1 antibody pembrolizumab and MEK inhibitor binimetinib, respectively.
The study is a global pivotal Phase 2/3 clinical trial evaluating the efficacy, safety and immunogenicity of SCB-2019 (CpG 1018/Alum), Clover's COVID-19 vaccine candidate.
Chinese insurance technology company Waterdrop Inc has officially debuted a digital clinical trial patient recruitment platform called "Yifan Recruitment", after trial operations for about half a year.
The patient recruiting platform has helped more than 10 leading pharmaceutical companies, such as Chia Tai Tianqing Pharmaceutical Group and Innovent, to recruit subjects for more than 60 new drug clinical trial projects in areas such as lung cancer, liver cancer, gynecological tumors and gastrointestinal tumors.
China's innovative medicine industry has been developing fast, due to facilitating policies and regulations, better access to capital investment, and the global shift of the pharmaceutical R&D outsourcing industrial chain in favor of China, which spurs the need for clinical trial patient recruitment.
However, recruiting patients traditionally relies on clinical trial research centers, and with the rapid growth of the number of clinical trial projects, those traditional channels cannot provide enough qualified subjects, especially with the impact of the pandemic.
On the other hand, people's lack of sufficient and correct knowledge of clinical trials in China also leads to increased difficulties in recruiting suitable patients for clinical trial projects, which often results in unsatisfactory recruitment rates and affects the development of new drugs.
Those patients often consult the crowdfunding platform on how to participate in clinical trial projects for new drugs to get free medication, it said, adding the launch of the recruiting platform aims to meet such needs.
Through the Yingfan Recruitment digital platform, patients can easily find the clinical trial projects that best match them.
The system will recommend the most suitable clinical trials to patients based on massive data crunching, to improve recruitment efficiency, reduce trial costs, improve the quality of clinical trial projects, and accelerate the approval and listing process of new drugs, the company said.
In the past six months, more than 30,000 patients with severe diseases have sought help from Yifan Recruit, and more than 5,000 of them have been matched to suitable clinical trial projects.
As some data showed only about 30 percent of adult cancer patients in China are willing to participate clinical trials, due to lack of awareness and correct knowledge, the recruiting platform has also established partnerships with many leading clinical trial facilities in China, to provide patient education and clinical trial project information.
Clover is currently advancing SPECTRA, a global pivotal Phase 2/3 clinical trial evaluating the efficacy, safety, and immunogenicity of SCB-2019 (CpG 1018/Alum), and expects interim data for vaccine efficacy around the middle of 2021.
According to CRRC Qingdao Sifang, the first EMU will be transported to Egypt for trial operations soon, and another 21 EMUs are expected to be delivered by the end of this year.