Example: "The two
isoforms of the protein have distinct functional properties due to differences in their amino acid sequences.
这两种蛋白质的异构体由于其氨基酸序列的不同而具有不同的功能特性。
Example: "Isoform-specific antibodies were used to identify and quantify the expression levels of different
isoforms in the cell lines.
使用针对特定异构体的抗体来识别和量化细胞系中不同异构体的表达水平。
Example: "Alternative splicing can lead to the production of multiple
isoforms from a single gene, increasing proteomic diversity.
可变剪接可以从单一基因产生多种异构体,从而增加蛋白质组的多样性。
Example: "The enzyme has three known
isoforms, each with slightly different substrate specificity.
这种酶有三种已知的异构体,每种在底物特异性上略有不同。
Example: "Isoform switching during development can significantly affect cellular behavior and contribute to tissue differentiation.
发育过程中异构体的转换可以显著影响细胞行为并促进组织分化。
Example: "RNA editing may generate new
isoforms that could play a critical role in disease pathogenesis."
RNA编辑可能生成新的异构体,在疾病发病机制中发挥关键作用。
Example: "Identifying which specific
isoform is upregulated or downregulated in cancer cells can help guide targeted therapies.
确定在癌细胞中哪些特定的异构体被上调或下调可以帮助指导靶向治疗策略。
Example: "The presence of certain
isoforms in the patient's genetic profile could serve as a predictive biomarker for drug response.
患者基因特征中某些异构体的存在可能作为药物反应的预测生物标志物。
Example: "Through gene sequencing, we discovered a novel
isoform that appears to be associated with resistance to chemotherapy.
通过基因测序,我们发现了一种与化疗耐药性有关的新异构体。
Example: "Differential expression of ion channel
isoforms contributes to the variation in electrophysiological properties among neurons.
离子通道异构体的差异表达导致了神经元间电生理特性的变化。
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