Cadherins are transmembrane proteins that play a crucial role in cell adhesion and tissue organization.
胶联素是一类跨膜蛋白,在细胞粘附和组织构建中起着关键作用。
The disruption of
cadherin function is often implicated in cancer development.
胶联素功能的丧失常常与癌症的发生有关。
Epithelial cells adhere to each other through a complex network of
cadherins.
上皮细胞通过复杂的胶联素网络相互粘附。
Beta-catenin is a protein that interacts with
cadherins to regulate the expression of target genes.
β-连环蛋白是一种与胶联素结合并调控靶基因表达的蛋白质。
Cadherin-mediated adhesion is essential for the formation and maintenance of tight junctions between cells.
由胶联素介导的粘附对于细胞间紧密连接的形成和维持至关重要。
Mutations in certain
cadherin genes have been linked to inherited diseases like EDS (Ehlers-Danlos syndrome).
某些胶联素基因突变与遗传疾病如埃勒斯-丹洛斯综合症有关。
The dynamics of
cadherin clustering during cell migration is tightly regulated.
细胞迁移过程中胶联素聚集的动力学受到严格调控。
In developmental biology,
cadherins guide cell sorting and tissue patterning.
在发育生物学中,胶联素参与细胞分类和组织模式的形成。
Researchers are exploring ways to enhance
cadherin-based therapies for treating conditions like osteoporosis.
研究人员正在探索增强基于胶联素的疗法以治疗如骨质疏松等病症。
The extracellular domain of
cadherin contains multiple recognition motifs that bind to neighboring cells.
胶联素的外周域包含多个识别位点,能与邻近细胞结合。
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