n.糖基（苷）化（作用）

Glycosylation is an essential post-translational modification that involves the attachment of glycans to proteins, thereby affecting their stability and function.
翻译：糖基化是一种关键的翻译后修饰过程，涉及将糖链附着到蛋白质上，从而影响其稳定性和功能。
N-linked glycosylation predominantly occurs on asparagine residues within proteins.
翻译：N-连接糖基化主要发生在蛋白质内部的天冬酰胺残基上。
The addition of sugar moieties during glycosylation can influence protein folding and cellular localization.
翻译：糖基化过程中糖基的添加可以影响蛋白质折叠和细胞定位。
Sialic acid content in glycosylation plays a crucial role in determining the half-life of certain therapeutic antibodies.
翻译：糖基化中的唾液酸含量在决定某些治疗性抗体半衰期方面起着至关重要的作用。
Abnormal glycosylation patterns have been associated with various diseases including cancer and autoimmune disorders.
翻译：异常的糖基化模式与包括癌症和自身免疫性疾病在内的多种疾病有关。
O-linked glycosylation often modifies serine or threonine residues in the extracellular domains of membrane proteins.
翻译：O-连接糖基化通常会修饰膜蛋白胞外区的丝氨酸或苏氨酸残基。
Protein glycosylation serves as a key regulatory mechanism in cell-cell recognition and adhesion processes.
翻译：蛋白质糖基化作为细胞间识别和粘附过程的关键调控机制。
Studying glycosylation profiles can provide valuable insights into the pathophysiology and progression of many diseases.
翻译：研究糖基化谱可以为许多疾病的病理生理学及其进展提供有价值的信息。
During the process of glycosylation, oligosaccharides are assembled and transferred to specific amino acids in the target protein.
翻译：在糖基化过程中，寡糖被组装并转移到目标蛋白质中的特定氨基酸上。
Defects in glycosylation pathways can lead to congenital disorders of glycosylation, which manifest as a broad range of clinical symptoms.
翻译：糖基化途径缺陷可导致先天性糖基化障碍，表现为一系列广泛的临床症状。