Hematopoietic stem cells (HSCs) are responsible for the production of all blood cell types.
血细胞生成干细胞负责生成所有类型的血细胞。
The
hematopoietic system is where blood cells are formed through the process of hematopoiesis.
血液系统是通过造血过程形成血细胞的地方。
Hematopoietic disorders can lead to anemia, leukemia, or other blood-related diseases.
造血功能障碍可导致贫血、白血病或其他血液相关疾病的发生。
Hematopoietic stem cell transplantation is a potentially life-saving treatment for some patients with blood cancers.
造血干细胞移植对于某些患有血液癌症的患者来说是一种潜在的救命疗法。
During embryonic development, the liver serves as a primary site for
hematopoietic activity.
在胚胎发育期间，肝脏是造血活动的主要场所。
Hematopoietic growth factors are used to stimulate the production of blood cells in patients undergoing chemotherapy.
造血生长因子用于刺激接受化疗的患者体内血细胞的生产。
The bone marrow is the primary
hematopoietic organ in adult humans.
骨髓是成人体内主要的造血器官。
Gene therapy targeting
hematopoietic stem cells has shown promise in treating inherited blood disorders.
针对造血干细胞的基因疗法在治疗遗传性血液病方面显示出巨大潜力。
Hematopoietic progenitor cells give rise to all mature blood cells, including red blood cells, white blood cells, and platelets.
造血祖细胞分化产生所有成熟的血细胞，包括红细胞、白细胞和血小板。
In a healthy individual,
hematopoietic cells originate from
hematopoietic stem cells located in the bone marrow.
在健康个体中，血细胞来源于位于骨髓内的造血干细胞。
Experts said that hematopoietic stem cell transplantation is often the main means for patients with hematologic malignancies, but about 30 to 70 percent of patients who undergo allogeneic hematopoietic stem cell transplantation will develop cGVHD.
专家表示，造血干细胞移植通常是血液系统恶性肿瘤患者的主要手段，但接受异基因造血干细胞植入的患者中，约有30%至70%会发生cGVHD。
The fund will be especially used for life and treatment support of patients with hematopoietic stem cell transplantation from impoverished families.
该基金将特别用于贫困家庭造血干细胞移植患者的生活和治疗支持。
Many studies have indicated that CAR-T therapy and hematopoietic stem-cell transplantation have a complementary effect when used together, and can achieve better efficacy.
许多研究表明，CAR-T疗法与造血干细胞移植联合使用具有互补作用，可以获得更好的疗效。
Professor Zhou Jianfeng, director of the Department of Hematology at Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, together with his team members, has applied the innovative combination of traditional autologous hematopoietic stem-cell transplantation with CAR-T therapy to the treatment of relapsed and refractory lymphoma.
华中科技大学同济医学院同济医院血液科主任周剑锋教授携团队成员，将传统自体造血干细胞移植与CAR-T疗法的创新结合应用于复发难治性淋巴瘤的治疗。
However, autologous hematopoietic stem-cell transplantation combined with high-dose chemotherapy can help CAR-T overcome this immunosuppressive microenvironment and promote the proliferation of CAR T-cells, thereby precisely killing cancer.
然而，自体造血干细胞移植结合大剂量化疗可以帮助CAR-T克服这种免疫抑制微环境，促进CAR T细胞的增殖，从而精确杀死癌症。
For lymphoma affecting the central nervous system in particular, the Department of Hematology of Tongji Hospital has led another clinical trial, specifically targeting in the long-term cure of patients in advanced stages and with CNS invasion after receiving the combined treatment of autologous hematopoietic stem-cell transplantation and CAR-T for the first time in the world.
特别是对影响中枢神经系统的淋巴瘤，同济医院血液科领导了另一项临床试验，专门针对在世界上首次接受自体造血干细胞移植和CAR-T联合治疗后，长期治愈晚期和中枢神经系统侵犯的患者。
In the past few decades, autologous hematopoietic stem-cell transplantation has played a fundamental role in the treatment of lymphoma.
在过去的几十年里，自体造血干细胞移植在淋巴瘤的治疗中发挥了基础性作用。
Case sharing: Combination of ASCT and CAR-T therapy improves CNS lymphoma patient survival benefitsOn Dec 21, Wu, a 52 years old woman, who suffered from DLBCL with multiple parts of the brain affected, received autologous hematopoietic stem-cell transplantation combined with CAR-T therapy at Tongji Hospital of Huazhong University of Science and Technology.
案例分享：ASCT和CAR-T联合治疗提高中枢神经系统淋巴瘤患者生存率12月21日，吴，一名52岁的女性，患有DLBCL，大脑多个部位受到影响，在华中科技大学同济医院接受了自体造血干细胞移植和CAR-T联合治疗。
"After a detailed evaluation, the team from the Department of Hematology of Tongji Hospital decided to adopt autologous hematopoietic stem-cell transplantation combined with CAR-T therapy for Wu.
“经过详细评估，同济医院血液科团队决定对吴采用自体造血干细胞移植结合CAR-T治疗。
After that, they infused autologous hematopoietic stem cells combined with sequential infusion of CAR T-cells.
之后，他们输注自体造血干细胞，并结合连续输注CAR T细胞。
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