n.血红蛋白病

Hemoglobinopathy is a group of inherited disorders that affect the structure or production of hemoglobin, the oxygen-carrying protein in red blood cells.
遗传性血红蛋白病是一类影响红细胞中氧载体蛋白质——血红蛋白结构或生成的遗传性疾病。
Sickle cell anemia is a common hemoglobinopathy which results in misshapen red blood cells and can lead to various health complications.
镰状细胞贫血是一种常见的血红蛋白病，导致红细胞形状异常，并可能引发各种健康并发症。
Thalassemia is another type of hemoglobinopathy characterized by reduced synthesis of one or more globin chains of hemoglobin.
地中海贫血是另一种血红蛋白病，其特征为血红蛋白的一种或多种珠蛋白链合成减少。
Hemoglobinopathy screening is often performed on newborns as part of routine genetic testing to identify potential disorders early.
血红蛋白病筛查经常作为常规基因检测的一部分在新生儿中进行，以便早期识别潜在疾病。
In some parts of the world where malaria is prevalent, certain hemoglobinopathies confer a survival advantage against the disease.
在疟疾盛行的一些地区，某些血红蛋白病会赋予患者对疾病的生存优势。
Hemoglobinopathy patients may experience symptoms such as fatigue, jaundice, and frequent infections due to their abnormal hemoglobin.
血红蛋白病患者可能会由于其异常血红蛋白而出现疲劳、黄疸和频繁感染等症状。
Genetic counseling plays a significant role for couples who have a family history of hemoglobinopathies to understand the risk of passing it on to their children.
对于有血红蛋白病家族史的夫妇来说，遗传咨询在理解将疾病遗传给子女的风险方面起着重要作用。
Hemoglobinopathy testing involves analyzing the structure and function of hemoglobin molecules through techniques like electrophoresis and molecular genetic testing.
血红蛋白病检测涉及通过电泳和分子遗传测试等技术分析血红蛋白分子的结构和功能。
Hemoglobinopathy treatments vary depending on the specific disorder and may include regular blood transfusions, chelation therapy, and in some cases, bone marrow transplantation.
血红蛋白病的治疗方法因具体病症不同而异，可能包括定期输血、螯合疗法，以及在某些情况下进行骨髓移植。
Early detection and management of hemoglobinopathies can significantly improve the quality of life and life expectancy for affected individuals.
早期发现并管理血红蛋白病可以显著提高受影响个体的生活质量和预期寿命。