异质性

Heteroplasmy refers to the presence of more than one type of mitochondrial DNA within a single cell or organism.
异质性指在一个单一细胞或生物体内存在多种类型的线粒体DNA。
In cases of heteroplasmy, both wild-type and mutated mtDNA can be found in an individual's cells.
在异质性情况下，个体的细胞中可以同时发现野生型和突变型的线粒体DNA。
The phenomenon of heteroplasmy is common in inherited mitochondrial diseases.
异质性现象在遗传性线粒体疾病中很常见。
Researchers identified heteroplasmy in the patient's muscle tissue, suggesting a maternal lineage disorder.
研究者在患者的肌肉组织中识别出异质性，表明其存在母系遗传紊乱。
Heteroplasmy levels can vary among different tissues within the same individual.
同一个体的不同组织之间的异质性程度可能会有所不同。
Accurate detection of heteroplasmy is crucial for understanding the pathogenesis of certain genetic disorders.
准确检测异质性对于理解某些遗传疾病的发病机制至关重要。
Heteroplasmy may lead to functional differences between cells, potentially contributing to disease phenotypes.
异质性可能导致细胞间功能差异，从而可能对疾病表型产生贡献。
Advances in next-generation sequencing have improved our ability to detect low-level heteroplasmy.
下一代测序技术的进步提高了我们检测低水平异质性的能力。
The study showed that the degree of heteroplasmy could influence the severity of symptoms in patients with mitochondrial disorders.
研究表明，异质性的程度会影响线粒体疾病患者症状的严重程度。
Heteroplasmy studies can provide insights into the inheritance patterns and potential treatment strategies for mitochondrial diseases.
异质性研究可以为线粒体疾病的遗传模式及其潜在治疗策略提供深入见解。