n.等臂染色体

The patient's karyotype revealed an isochromosome 12p, which is characteristic of some cases of therapy-related acute myeloid leukemia.
患者的染色体组型显示出12号染色体的等臂染色体，这是某些治疗相关急性髓系白血病病例的特点。
Isochromosome formation can lead to unbalanced translocations and cause genomic disorders.
等臂染色体的形成可能导致不平衡易位，并引发基因组疾病。
In the study, an isochromosome 18q was identified in a fetus with congenital heart defects.
在研究中，发现一例先天性心脏病胎儿存在18号染色体的等臂染色体。
Isochromosomes result from errors during cell division that lead to unequal distribution of genetic material.
等臂染色体是细胞分裂过程中遗传物质分配不均错误的结果。
A case report detailed the presence of an isochromosome Xq as a causative factor for Turner syndrome.
一份案例报告详细描述了X染色体q臂等臂染色体作为特纳综合症致病因素的存在。
Detection of an isochromosome 21 may be indicative of B-cell chronic lymphocytic leukemia.
检测到21号染色体的等臂染色体可能是慢性B细胞淋巴细胞性白血病的标志。
Isochromosomes often arise due to centromere misdivision or subsequent DNA replication errors.
等臂染色体通常由于着丝粒错分或随后的DNA复制错误而产生。
The isochromosome seen in this case led to duplication of certain genes and deletion of others, causing a rare genetic disorder.
本案例中的等臂染色体导致某些基因重复和其它基因缺失，从而引发了罕见的遗传性疾病。
Advances in molecular cytogenetics have enabled more accurate identification and characterization of isochromosomes.
分子细胞遗传学的进步使我们能更准确地识别和表征等臂染色体。
The diagnosis of isochromosome should always be confirmed by molecular techniques such as FISH or array CGH.
等臂染色体的诊断应始终通过如FISH（荧光原位杂交）或阵列比较基因组杂交等分子技术来确认。