A
nucleophile is an atom or molecule that donates an electron pair to form a chemical bond.
翻译:亲核试剂是一种能够提供一对电子以形成化学键的原子或分子。
Nucleophiles typically have a negative charge or an unshared pair of electrons, making them highly reactive.
翻译:亲核试剂通常带有负电荷或拥有一对未共享电子,因此具有高度反应性。
In SN2 reactions, the
nucleophile attacks from the backside of the substrate to replace the leaving group.
翻译:在SN2反应中,亲核试剂从底物的背面攻击并取代离去基团。
The strength of a
nucleophile is influenced by its size and electronegativity.
翻译:亲核试剂的强度受到其大小和电负性的影响。
Hydroxide ion (OH-) is a strong
nucleophile in aqueous solutions.
翻译:氢氧根离子(OH-)在水溶液中是一种强亲核试剂。
Alkoxide ions are excellent
nucleophiles due to their high affinity for protons.
翻译:由于对质子有很高的亲和力,醇盐离子是优秀的亲核试剂。
Amines can act as
nucleophiles in substitution reactions with alkyl halides.
翻译:胺类可以在与卤代烷的取代反应中作为亲核试剂。
Sulfur-based
nucleophiles, such as thiols, participate in various biological processes.
翻译:硫基亲核试剂,如硫醇,参与各种生物过程。
Phosphate groups often function as
nucleophiles in phosphorylation reactions within cells.
翻译:磷酸盐基团经常在细胞内的磷酸化反应中充当亲核试剂。
The rate of a reaction involving a
nucleophile increases with increasing concentration of the
nucleophile.
翻译:涉及亲核试剂的反应速率随着亲核试剂浓度的增加而增加。
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