Oncogenesis is the process by which normal cells transform into cancerous cells.
癌变发生的过程,正常细胞转化为恶性肿瘤细胞。
The study of
oncogenesis focuses on understanding the genetic changes that initiate cancer development.
研究癌症发生机制,关注引发癌症的基因变化。
Tumor suppressor genes play a crucial role in
oncogenesis, as their inactivation can lead to uncontrolled cell growth.
抑癌基因在癌变中至关重要,因为它们失活可能导致细胞失控增长。
Environmental factors, such as smoking and exposure to carcinogens, can trigger
oncogenesis.
环境因素如吸烟和接触致癌物可以触发癌变过程。
Oncogenes, when activated abnormally, can turn a single cell into a cancerous mass.
原癌基因一旦异常激活,可以使单个细胞变成肿瘤实体。
Cancer chemotherapy aims at inhibiting
oncogenesis or slowing its progression by targeting cancer cells.
癌症化疗通过靶向癌细胞来抑制或延缓其发生发展。
In some cases, oncogenes can be mutated into tumor suppressors, a phenomenon known as oncogene addiction.
在某些情况下,原癌基因可能突变为抑癌基因,这种现象被称为"原癌基因依赖性"。
Understanding the molecular mechanisms of
oncogenesis can pave the way for personalized cancer treatments.
理解癌症发生机制的分子层面有助于个性化癌症治疗的发展。
Animal models have been instrumental in advancing our understanding of
oncogenesis.
动物模型在深化我们对癌症发生机制的理解上发挥了重要作用。
Early detection and prevention strategies are critical to interrupting
oncogenesis before it progresses to advanced stages.
早期发现和预防策略对于在癌症发展到晚期前阻止其发生至关重要。
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