外显率

The penetrance of the disease in this family is nearly 100%, meaning that almost everyone with the gene mutation will develop the condition.
这个家族中该疾病的外显率接近100%，这意味着几乎每个携带基因突变的人都会发展出这种病症。
A high penetrance allele can significantly increase the risk of developing a particular disorder.
高外显率等位基因可以显著增加患某种特定疾病的风险。
Penetrance for Huntington's disease is complete, which means that all individuals who inherit the faulty gene will eventually show symptoms.
帕金森病的外显率是完全的，这意味着所有遗传到缺陷基因的个体最终都会表现出症状。
Understanding the variable penetrance of some genetic mutations is crucial for predicting an individual’s risk of developing a disease.
理解某些基因突变的可变外显性对于预测个体患病风险至关重要。
The penetrance of the BRCA1 mutation in breast cancer susceptibility varies between populations and can be influenced by other genetic and environmental factors."
BRCA1基因在乳腺癌易感性中的外显率在不同人群中有所不同，且可能受到其他遗传和环境因素的影响。
Researchers are studying the incomplete penetrance of autism spectrum disorders to better understand why some people with the genetic markers don't develop the condition.
研究人员正在研究自闭症谱系障碍的不完全外显性，以更好地理解为什么一些带有遗传标记的人并未发展出此病症。
The low penetrance of the ApoE4 allele in Alzheimer's disease indicates that not all carriers will develop the disease.
阿尔茨海默病中ApoE4等位基因的低外显率表明并非所有携带者都会患上此病。
Environmental factors may modify the penetrance and expressivity of certain genetic traits.
环境因素可能会改变某些遗传特征的外显率和表现度。
Although there is a strong genetic component, the penetrance of schizophrenia is less than 100% due to complex interactions with other genes and environmental triggers.
尽管精神分裂症有强烈的遗传成分，但由于与其他基因及环境触发因素的复杂交互作用，其外显率低于100%。
The study found that while the penetrance of the gene mutation was high among affected families, some non-carriers also developed the disease suggesting additional contributing factors.
研究发现，在受影响的家庭中，虽然该基因突变的外显率很高，但一些非携带者也发展出了这种疾病，这提示还有其他促成因素。