n.聚腺苷酸化

The process of polyadenylation is essential for the stability and translation efficiency of mRNA molecules.
多聚腺苷酸化过程对于mRNA分子的稳定性和翻译效率至关重要。
During transcription, the addition of a poly(A) tail to the 3' end of an mRNA molecule is known as polyadenylation.
在转录过程中，在mRNA分子3'末端添加多聚腺苷酸尾的过程被称为多聚腺苷酸化。
In eukaryotes, cleavage and polyadenylation of pre-mRNA occur in the nucleus before export to the cytoplasm.
在真核生物中，pre-mRNA的剪切和多聚腺苷酸化在转运到细胞质之前在细胞核内发生。
The polyadenylation signal sequence AAUAAA is recognized by specific proteins to initiate the polyadenylation process.
特异性的蛋白质识别多聚腺苷酸化信号序列AAUAAA以启动多聚腺苷酸化过程。
Incorrect polyadenylation can lead to truncated proteins or altered gene expression patterns.
错误的多聚腺苷酸化可能导致截短的蛋白质或改变基因表达模式。
RNA polymerase adds a string of adenine nucleotides to the end of the transcript during polyadenylation.
在多聚腺苷酸化过程中，RNA聚合酶会在转录本末端添加一系列腺苷酸核苷酸。
A mutation in the polyadenylation site may result in the failure of proper mRNA processing and degradation.
多聚腺苷酸化位点的突变可能导致mRNA无法正常加工和降解。
The length of the poly(A) tail can affect the stability and half-life of mRNA in the cell.
多聚腺苷酸尾的长度会影响细胞内mRNA的稳定性和半衰期。
The mechanism of polyadenylation involves the recognition of cis-acting elements and trans-acting factors.
多聚腺苷酸化的机制涉及顺式作用元件和反式作用因子的识别。
Many viruses also utilize host cell polyadenylation machinery to regulate their own gene expression.
许多病毒也利用宿主细胞的多聚腺苷酸化机制来调节其自身的基因表达。