Secretin is a hormone produced by the small intestine that stimulates the secretion of pancreatic juice rich in bicarbonate ions.
秘密素是一种由小肠产生的激素，能刺激分泌富含碳酸氢根离子的胰液。
The administration of
secretin can be used as a diagnostic tool to assess pancreatic function in certain clinical settings.
在某些临床情况下，使用秘密素作为诊断工具可以评估胰腺功能。
Secretin release is triggered by the presence of acidic chyme entering the duodenum from the stomach.
胃酸性食糜进入十二指肠会触发秘密素的释放。
After a meal,
secretin helps regulate the pH balance in the small intestine by promoting the release of alkaline pancreatic juices.
饭后，秘密素通过促进碱性胰液的释放帮助调节小肠中的pH平衡。
In addition to its role in digestion,
secretin also influences the regulation of blood glucose levels and appetite.
除了在消化中的作用外，秘密素还影响血糖水平和食欲的调节。
The discovery of
secretin in 1902 by William Bayliss and Ernest Starling was a milestone in the understanding of hormonal regulation in the body.
1902年，威廉·贝利斯和欧内斯特·斯塔林发现秘密素，这是理解体内激素调节的一个里程碑。
Secretin acts on the pancreas and liver, causing them to increase the production of bicarbonate and bile, respectively, to neutralize stomach acids.
秘密素作用于胰腺和肝脏，分别促使它们增加碳酸氢盐和胆汁的产生，以中和胃酸。
Studies have suggested that abnormalities in
secretin signaling might be implicated in certain gastrointestinal disorders, such as irritable bowel syndrome.
研究表明，秘密素信号传导的异常可能与某些胃肠疾病（如肠易激综合症）有关。
The effect of
secretin on increasing intestinal motility aids in the propulsion of food through the digestive tract.
秘密素增加肠道蠕动的效果有助于食物在消化道中的推进。
Researchers are exploring the potential therapeutic uses of
secretin for conditions like autism spectrum disorder, though evidence remains inconclusive.
研究人员正在探索秘密素在自闭症谱系障碍等疾病中的潜在治疗用途，尽管证据仍不明确。
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