选择素

Selectin proteins play a crucial role in leukocyte adhesion and immune cell migration during inflammation.
选择素蛋白在炎症过程中对白细胞黏附和免疫细胞迁移起着关键作用。
The selectin family, including L-selectin and P-selectin, are glycoproteins found on the surface of endothelial cells.
选择素家族，如L-选择素和P-选择素，是存在于内皮细胞表面的糖蛋白。
During an infection, pathogens can exploit selectins to gain entry into host cells.
在感染过程中，病原体可以利用选择素进入宿主细胞。
Researchers have developed drugs targeting selectins to inhibit their function in diseases like arthritis.
研究人员已经开发出针对选择素的药物，以抑制其在类风湿性关节炎等疾病中的功能。
E-selectin is upregulated in response to tissue injury, facilitating the recruitment of immune cells to the site of damage.
E-选择素在组织损伤时上调，促进免疫细胞向损伤部位招募。
Platelets express P-selectin, which binds to von Willebrand factor and helps initiate blood clotting.
血小板表达P-选择素，它与血管性血友病因子结合，有助于启动血液凝固过程。
L-selectin is primarily involved in the initial steps of leukocyte rolling along the endothelium, before firm adhesion occurs.
L-选择素主要参与白细胞在内皮细胞上滚动的初期步骤，然后才会发生牢固粘附。
Selectins are a class of adhesion molecules that mediate the first contact between leukocytes and endothelial cells.
选择素是一类介导白细胞与内皮细胞初次接触的粘附分子。
The interaction between selectins and their ligands is essential for the process of leukocyte extravasation from the bloodstream.
选择素与其配体之间的相互作用对于白细胞从血液中溢出的过程至关重要。
In cancer, altered expression of selectins can contribute to tumor cell invasion and metastasis.
在癌症中，选择素表达的改变可能促进肿瘤细胞的侵袭和转移。