紫杉烷

Paclitaxel, a well-known taxane, is widely used in the treatment of various cancers including ovarian and breast cancer.
紫杉醇是一种著名的紫杉烷类药物，被广泛应用于治疗包括卵巢癌和乳腺癌在内的多种癌症。
Taxanes, such as docetaxel, are chemotherapy agents that disrupt microtubule dynamics leading to cell cycle arrest.
多西他赛等紫杉烷类药物是化疗药物，它们通过干扰微管蛋白动力学导致细胞周期停滞。
The taxane-based drug nab-paclitaxel was found to significantly improve response rates in patients with advanced pancreatic cancer.
基于紫杉烷类的药物白蛋白结合型紫杉醇在晚期胰腺癌患者中被发现能显著提高反应率。
Taxanes exhibit their antineoplastic effects by promoting the assembly and stabilization of microtubules in cells.
紫杉烷类药物通过促进细胞内微管蛋白的装配和稳定来发挥其抗肿瘤效应。
In the field of oncology, taxanes have been pivotal in advancing the treatment of metastatic prostate cancer.
在肿瘤学领域，紫杉烷类药物在转移性前列腺癌治疗的进展中起到了关键作用。
A phase III clinical trial demonstrated improved overall survival when combining taxane therapy with immunotherapy for certain lung cancer patients.
一项III期临床试验显示，在某些肺癌患者中，紫杉烷类疗法与免疫疗法联合使用可以提高总生存率。
Despite being highly effective, taxanes can cause severe side effects like peripheral neuropathy and myelosuppression.
尽管紫杉烷类药物效果显著，但可能导致严重的副作用，如周围神经病变和骨髓抑制。
Novel taxane analogs are under investigation for potential use against multidrug-resistant tumors.
新型紫杉烷类似物正在研究中，以用于对抗多重耐药性肿瘤。
Due to its poor water solubility, taxanes are often formulated with solubilizing agents for intravenous administration.
由于水溶性差，紫杉烷类药物通常会配制含有溶解剂的制剂以便静脉给药。
The discovery of taxanes from yew trees revolutionized the treatment landscape for many solid tumor malignancies.
从红豆杉树中发现紫杉烷类化合物，革新了许多实体瘤恶性肿瘤的治疗方法。