单倍体不足

Haploinsufficiency of the tumor suppressor gene BRCA1 increases susceptibility to breast cancer."
BRCA1肿瘤抑制基因的单倍体不足会增加乳腺癌的易感性。
The haploinsufficiency of the FOXP2 gene is associated with speech and language disorders."
FOXP2基因的单倍体不足与言语和语言障碍有关联。
In Down syndrome, the partial or complete haploinsufficiency of chromosome 21 genes contributes to the intellectual disability phenotype.
在唐氏综合症中，第21号染色体基因的部分或完全单倍体不足导致了智力障碍的表现型。
This patient's condition may be due to the haploinsufficiency of the gene responsible for normal development of the heart.
这位病人的状况可能是由于负责心脏正常发育的基因的单倍体不足所致。
Haploinsufficiency of the RUNX1 gene has been linked to familial platelet disorder with a propensity to develop acute myeloid leukemia."
RUNX1基因的单倍体不足已被关联到有急性髓系白血病倾向的家族性血小板疾病。
PTEN haploinsufficiency can lead to a range of developmental and oncogenic abnormalities."
PTEN基因的单倍体不足可能导致一系列发育异常和致癌性异常。
A common mechanism in genetic diseases is haploinsufficiency, where only one functional copy of a gene is present.
遗传疾病的一个常见机制是单倍体不足，即只存在一个功能性的基因拷贝。
Scientists have identified haploinsufficiency of the SHH gene as a cause of holoprosencephaly.
科学家已经确定SHH基因的单倍体不足是导致全前脑无裂畸形的原因。
Studies show that haploinsufficiency of the NF1 gene leads to neurofibromatosis type 1."
研究表明，NF1基因的单倍体不足会导致I型神经纤维瘤病。
Individuals with haploinsufficiency for the SMAD4 gene often present with juvenile polyposis syndrome."
SMAD4基因单倍体不足的个体常常表现出青少年息肉病综合征。