免疫蛋白酶体

The immunoproteasome is an essential component of the immune system, responsible for breaking down damaged proteins.
免疫蛋白酶体是免疫系统中必不可少的部分，负责分解受损的蛋白质。
In cancer, dysregulation of the immunoproteasome leads to the accumulation of abnormal proteins and contributes to tumor growth.
在癌症中，免疫蛋白酶体的失调导致异常蛋白质积累，促进了肿瘤生长。
Immunoproteasomes are involved in the presentation of antigens to T-cells, initiating an immune response.
免疫蛋白酶体参与将抗原呈递给T细胞的过程，启动免疫反应。
Cancer therapy often targets the proteasome, as it's a primary site for protein degradation that can be hijacked by tumors.
癌症治疗常常针对蛋白酶体，因为它是一个被肿瘤利用进行蛋白质降解的主要部位。
The study of immunoproteasome function has led to new insights into autoimmune diseases.
研究免疫蛋白酶体的功能为理解自身免疫疾病提供了新的见解。
Pharmacological inhibition of the immunoproteasome can be used to suppress inflammation in certain inflammatory conditions.
通过抑制免疫蛋白酶体，可以在某些炎症条件下抑制炎症反应。
The degradation products from the immunoproteasome can be detected in body fluids, indicating disease activity.
免疫蛋白酶体的降解产物可在体液中检测到，作为疾病活动的指标。
Immunoproteasomes are highly conserved across species, playing a universal role in protein turnover.
免疫蛋白酶体在物种间高度保守，执行着普遍的蛋白质周转功能。
A new drug candidate is being developed to target specific immunoproteasome subtypes for treatment of autoimmunity.
正在研发一种新药，目标是针对特定免疫蛋白酶体亚型来治疗自身免疫病。
Understanding the mechanisms by which immunoproteasomes regulate inflammation is crucial for developing novel therapies.
理解免疫蛋白酶体如何调节炎症对于开发新疗法至关重要。