adj.不可挽回的，无法纠正的，不可治愈的

The damage to the ancient statue was found to be irremediable, leaving conservators with no choice but to preserve its current state.
这座古老雕像的损坏被发现是无法修复的，留给保护人员的唯一选择就是保持其现状。
The doctor concluded that the patient's condition had progressed to an irremediable stage, making further treatment futile.
医生断定病人的情况已经发展到无法挽回的阶段，再进行治疗也是徒劳。
The environmental pollution in some areas has reached an irremediable level, necessitating immediate and drastic measures to prevent further deterioration.
某些地区的环境污染已经达到了无可救药的程度，急需立即采取严厉措施以防止情况进一步恶化。
Their relationship had deteriorated to such an irremediable point that reconciliation seemed impossible.
他们的关系已经恶化到了无可挽回的地步，和解似乎是不可能的了。
The mistake in the calculations was so fundamental that it led to irremediable consequences for the entire project.
计算中的错误非常根本，导致了对整个项目不可挽回的后果。
The effects of long-term neglect on the historic building were irremediable, resulting in its eventual demolition.
长期忽视对这座历史建筑的影响是无法补救的，最终导致了它的拆除。
The data loss due to the hardware failure was irremediable, emphasizing the importance of regular backups.
硬件故障导致的数据丢失是无法挽回的，这强调了定期备份的重要性。
The company's reputation suffered an irremediable blow after the scandal, leading to a significant drop in sales.
丑闻之后，公司的声誉受到了无法挽回的打击，导致销售额大幅下降。
The damage to the ecosystem from the oil spill proved to be irremediable, causing irreversible changes to marine life.
油污对生态系统的损害证明是无法修复的，给海洋生物带来了不可逆的变化。
The misunderstanding between the friends was allowed to fester for too long, turning it into an irremediable rift.
朋友之间的误会未能及时解决，久而久之演变成了无法弥补的裂痕。