毒代动力学

The study investigated the toxicokinetics of the compound in rats, which refers to how the body absorbs, distributes, metabolizes, and excretes toxins.
研究调查了该化合物在大鼠体内的毒代动力学，即身体如何吸收、分布、代谢和排泄毒素。
Toxicokinetics analysis is crucial for understanding the dynamic behavior of chemicals within an organism once exposed.
毒代动力学分析对于理解化学物质暴露后在生物体内动态行为至关重要。
To predict potential human health risks, we conducted a toxicokinetic assessment of the new pesticide in laboratory animals.
为了预测潜在的人类健康风险，我们在实验动物中进行了新型农药的毒代动力学评估。
In vitro studies were carried out to estimate the toxicokinetics profile of the drug candidate before proceeding to clinical trials.
在进行临床试验之前，我们进行了体外研究以估算候选药物的毒代动力学特征。
By studying the toxicokinetics of the substance, scientists can determine its half-life and understand its persistence in living organisms.
通过研究物质的毒代动力学，科学家可以确定其半衰期并了解其在生物体内的持久性。
A comprehensive toxicokinetics study was performed to evaluate the bioavailability and elimination pathway of the environmental contaminant.
为了评估环境污染物的生物利用度和消除途径，进行了全面的毒代动力学研究。
Understanding the toxicokinetics of a chemical helps in predicting dose-response relationships and assessing potential adverse effects.
理解化学品的毒代动力学有助于预测剂量-反应关系以及评估潜在的不良影响。
The toxicokinetics parameters such as absorption rate constant and volume of distribution help to establish safe exposure limits for pharmaceuticals.
诸如吸收速率常数和分布容积等毒代动力学参数有助于建立药品的安全接触限值。
The toxicokinetics data obtained from animal experiments will be extrapolated to humans to assess potential risks associated with long-term exposure.
从动物实验获得的毒代动力学数据将推断至人类，以评估长期接触相关的潜在风险。
It is essential to consider both pharmacokinetics and toxicokinetics when designing drugs to ensure their efficacy and safety profiles.
在设计药物时，考虑到药代动力学和毒代动力学都是至关重要的，以确保药物的有效性和安全性。