Get to know the
candidates on the short list.
了解短名单上的候选人。
Mark is the best
candidate for the post of chairman。
马克是董事长职位的最佳候选人。
He was the only
candidate; therefore, he was elected.
他是唯一的候选人,因此他当选了。
During the CIIE, Boehringer Ingelheim also exhibited a new drug candidate at the Phase-3 clinical trial for treating idiopathic pulmonary fibrosis, a rare and chronic lung disease.
在CIIE期间，勃林格殷格翰还在治疗特发性肺纤维化（一种罕见的慢性肺病）的3期临床试验中展示了一种新的候选药物。
The company has announced its formulation of a candidate COVID-19 vaccine, with clinical trials scheduled to kick off in China this year.
该公司宣布了其候选新冠肺炎疫苗的配方，临床试验计划于今年在中国启动。
Progress has also been made with the development candidate aflibercept 8 mg, which was compared with Eylea™ containing 2xa0mg of aflibercept in two pivotal studies.
与Eylea相比，开发候选药物8 mg的阿法西普也取得了进展™ 在两项关键研究中含有2xa0mg的阿法西普。
The financial threshold for setting up a finance company has been raised in line with China's economic status, with higher asset, revenue, profit and paid-in capital requirements for candidate corporate groups, according to the draft document.
根据文件草案，设立财务公司的财务门槛已根据中国的经济状况提高，候选企业集团的资产、收入、利润和实收资本要求更高。
The mRNA company will accelerate the late-stage development and registration of its potentially best-in-class mRNA COVID-19 vaccine candidate, PTX-COVID19-B, and continue the development of a second-generation COVID-19 vaccine with broad spectrum activity designed to be effective against but not limited to the Omicron variants, as well as two Collaboration Project with Providence that target new mRNA based vaccines, Everest said.
mRNA公司将加快其潜在的最佳mRNA新冠肺炎候选疫苗PTX-COVID19-B的后期开发和注册，并继续开发具有广谱活性的第二代新冠肺炎疫苗，该疫苗旨在有效对抗但不限于奥密克戎变异株，以及与普罗维登斯的两个针对新型信使核糖核酸疫苗的合作项目，Everest说。
This year, Yang was selected as a candidate for the foundation's project to empower intangible cultural heritage entrepreneurship and address the challenges faced by ethnic minority rural women, enabling them to live a good life without leaving their hometown.
今年，杨被选为该基金会项目的候选人，该项目旨在为非物质文化遗产创业赋能，并应对少数民族农村妇女面临的挑战，使她们能够不离开家乡就过上好日子。
The agreement said Adagene, founded in Suzhou, Jiangsu province in 2012, will be responsible for early-stage research activities to develop versions of Sanofi candidate antibodies, using Adagene's proprietary technology.
协议称，2012年在江苏省苏州市成立的阿达吉恩将负责利用阿达吉恩的专有技术开发赛诺菲候选抗体的早期研究活动。
Clover Biopharmaceuticals, a Chinese clinical-stage biopharma company developing vaccines and oncology drugs, announced on Wednesday that its protein-based COVID-19 vaccine candidate was found to be 67 percent effective against COVID-19 of any degree of severity and 79 percent against the highly infectious Delta variant in a large late-stage trial.
The vaccine, deploying proteins on the coronavirus to stimulate immunity against COVID-19, is also the first COVID-19 vaccine candidate in the world to demonstrate in a randomized trial significantly reduced risk of COVID-19 disease in previously infected individuals, a growing and increasingly important population as the virus continues to spread worldwide, the company claimed.
"Based on our pioneering data, we believe that SCB-2019 (the vaccine candidate) could be utilized as an important tool to combat this pandemic, and we remain dedicated to expediting the availability and equitable access of our COVID-19 vaccine candidate for global distribution," Liang said.
According to an advance purchase agreement with Gavi, or the Vaccine Alliance, the company will provide up to 414 million doses of its protein-based COVID-19 vaccine candidate for procurement through the COVAX facility.
The company said the new drug candidate to treat drug-resistant CML patients has been granted orphan drug and fast track designations by the United States Food and Drug Administration.
It is also doubling down on a talent training system dubbed Fast Trak, looking to increase the venue, personnel and financial input to construct Asia's largest biopharma candidate hub and intelligent manufacturing showroom.
Providence's lead mRNA COVID-19 vaccine candidate, which is currently in Phase 2 clinical trials, has demonstrated it is generally safe and well-tolerated and that the dosed subjects have high neutralization titers against the original strain of SARS-CoV-2 in an S protein-typed pseudovirus assay.
A key drug candidate was developed for the treatment of drug-resistant chronic myeloid leukemia, which affects an estimated 10,000 patients in the country each year, said Yang Dajun, chairman and CEO of Ascentage Pharma.
Beijing-based YishengBio Co Ltd announced during the fair that its PIKA recombinant COVID-19 vaccine, an innovative prophylactic and therapeutic vaccine candidate against multiple SARS-CoV-2 variants, has won clinical trial approval from health authorities in the United Arab Emirates to treat patients with mild to moderate SARS-CoV-2 infections.
According to Chen, the company's recombinant vaccine candidate has finished first and second-phase clinical trials in China with favorable results.
One of the major exhibits at the fair will be its core drug candidate developed for the treatment of drug-resistant chronic myeloid leukemia (CML), which afflicts an estimated 10,000 patients in the country each year, Yang said.
Altogether, four of the company's candidate drugs have been granted 12 orphan drug qualifications by the US FDA so far, allowing it to become the enterprise with the largest number of such qualifications domestically, according to the company.
At the fair in Beijing, the company will ink strategic collaborations with different players in the health sector, including a precise testing provider, and insurance companies, to prepare to help patients use the right therapy, improve drug accessibility, and ease patients' financial burden after the drug candidate's market approval, which may be expected in the fourth quarter of this year.
US-based Biogen Inc and Hong Kong-listed Chinese mainland biopharma startup InnoCare Pharma Ltd announced on Monday that they have entered into a license and collaboration agreement for orelabrutinib, a drug candidate currently in a multi-country, placebo-controlled Phase 2 trial for the potential treatment of multiple sclerosis, a rare disease of the nervous system characterized by loss of feeling and control of movement and speech.
Wang Yinxiang, chairman and CEO of Jacobio, said the company is the second drug developer in the world to engage in clinical development of an SHP2 inhibitor drug candidate, following Novartis.
The study is a global pivotal Phase 2/3 clinical trial evaluating the efficacy, safety and immunogenicity of SCB-2019 (CpG 1018/Alum), Clover's COVID-19 vaccine candidate.
Chinese clinical-stage biotech Clover Biopharmaceuticals and Nasdaq-listed Dynavax Technologies Corp, a biopharmaceutical company focused on developing and commercializing novel vaccines, announced on Wednesday a commercial supply agreement of Dynavax's CpG 1018TM advanced adjuvant for use in Clover's protein-based COVID-19 vaccine candidate, SCB-2019 (CpG 1018/Alum).
According to the agreement, the company is to provide up to 414 million doses of its protein-based COVID-19 vaccine candidate for procurement through the COVAX facility.
Pending an Emergency Use Listing from the World Health Organization for Clover's COVID-19 vaccine candidate, Clover will make an initial 64 million doses available for procurement through the COVAX facility in 2021.
"The pandemic continues to have a profound impact on the world, and we remain dedicated to expediting the availability of our COVID-19 vaccine candidate for procurement and global distribution," Liang said.
Insilico Medicine demonstrated the first case of AI identifying a novel target for a major pulmonary disease, generating novel molecules for that novel target, and completing the preclinical experiments required to nominate a preclinical candidate in under 18 months.
This forces the CEO to either look for another candidate, or dedicate their energies toward convincing their unwilling first-choice successor.
This can manifest in many different ways, from potential successors being more willing to learn from CEOs' experience, to enlarging the pool of viable successor candidates, reducing familial infighting over the succession, and generally creating a more harmonious environment for knowledge transfer and the strategic consideration of who is the most suitable candidate for the job.
Chinese clinical-stage biotech Clover Biopharmaceuticals and Nasdaq-listed biopharmaceutical company Dynavax Technologies Corporation announced on Wednesday the first participants have been dosed in Clover's global Phase 2/3 clinical trial evaluating the efficacy, safety and immunogenicity of its protein-based S-Trimer COVID-19 vaccine candidate adjuvanted with Dynavax's CpG 1018 plus alum.
The global Phase 2/3 trial is a double-blind, randomized, controlled study of the adjuvanted S-Trimer COVID-19 vaccine candidate in a two-dose regimen, given 21 days apart.
Joshua Liang, CEO of Clover Biopharmaceuticals, said there is still a significant need in many global communities for COVID-19 vaccines and should the Phase 2/3 interim analysis be favorable, the company will work closely with regulatory authorities worldwide to make the S-Trimer COVID-19 vaccine candidate available as soon as possible.
Ryan Spencer, CEO of Dynavax, said Clover's adjuvanted vaccine candidate has the potential to be an important additional solution to address worldwide demand, since it can be manufactured at large scale and stored at standard refrigeration temperature.
In December 2020, Clover reported positive clinical data from its Phase 1 trial, demonstrating its protein-based COVID-19 S-Trimer vaccine candidate in combination with Dynavax's CpG 1018 induces strong immune response, including neutralizing antibodies and cell-mediated immunity, as well as favorable safety and tolerability profiles in the adult and elderly participants.
The vaccine candidate is expected to be stable long-term under standard refrigeration conditions and has demonstrated stability at room temperature for at least two months, making it suitable for global distribution.
Clover expects to initiate a global Phase 2/3 efficacy trial for SCB-2019 (S-Trimer), its COVID-19 vaccine candidate, in the first half of 2021 and has initiated production planning for potentially hundreds of millions of vaccine doses in 2021.
Michael Yi, co-CIO and partner of Hillhouse Capital, said Clover has had a tremendous year of growth with the rapid advancement of the COVID-19 S-Trimer vaccine candidate through clinical development, and its robust and differentiated pipeline of vaccines and biologic therapeutics hold great promise to make a difference in other areas.
Sinovac Biotech Ltd, a leading provider of biopharmaceutical products in China, announced Monday that Sinovac Life Sciences Co Ltd, a Sinovac subsidiary, has secured approximately $500 million in funding for further development, capacity expansion and manufacturing of CoronaVac, its COVID-19 vaccine candidate, as well as conduct other development and operational activities.
"We have made significant progress in the development of our COVID-19 vaccine candidate CoronaVac, which has reached critical milestones in clinical trials in Asia and Latin America," said Weidong Yin, chairman, president and CEO of Sinovac.
xa0xa0In China,xa0the phase I/II trials were conducted with results showing the vaccine candidate can induce neutralizing antibodies among over 90 percent of volunteers who received two doses of vaccination in both adults and the elderly.
German biotechnology company BioNTech SE and Shanghai Fosun Pharmaceutical (Group) Co Ltd jointly announced on Wednesday that their lead mRND COVID-19 vaccine candidate BNT162b2 will be evaluated in a phase 2 clinical trial.
The online recruitment of volunteers will commence with the recruitment of 960 healthy participants, aged between 18 and 85, to assess the safety and immunogenicity of the vaccine candidate and to support future biologic license applications in China.
Another highlight was Cytiva's support of Clover Biopharmaceuticals to scale up the output of its vaccine candidate, paving the way for the production of COVID-19 vaccines in the future.
Statistics from World Health Organization showed that a total of 44 candidate vaccines worldwide had entered clinical evaluations as of Oct 19, among which 10 were at the final phase of testing.
The Coalition for Epidemic Preparedness Innovations, an innovative partnership launched at Davos in 2017 between public, private, philanthropic and civil organizations to develop vaccines to stop future epidemics, announced Tuesday that it will fund the development of the protein-based S-Trimer COVID-19 vaccine candidate by China's Sichuan Clover Biopharmaceuticals Inc through to licensure, including a global pivotal Phase 2/3 efficacy clinical study beginning before the end of 2020, if the vaccine is proven to be safe and effective.
The coalition's total investment in Clover's S-Trimer vaccine candidate will be up to $328 million, including previously announced commitments of $69.5 million, which have funded preclinical studies and Phase 1 clinical trials, preparations for the global pivotal Phase 2/3 efficacy study and initial manufacturing scale-up activities.
The expanded partnership is a result of Clover's successful early stage clinical development of the S-Trimer vaccine candidate.
Promising preclinical and preliminary Phase 1 data – which will be published in a peer-reviewed publication in the near future - indicate that S-Trimer is well-tolerated and produces strong neutralizing antibody and Th1-biased cell-mediated immune responses, which merit ongoing evaluation of the vaccine candidate, Clover said in a press release.
It will provide full funding for a global pivotal Phase 2/3 efficacy clinical trial of S-Trimer, which is expected to begin before the end of 2020 and aims to generate the necessary safety and efficacy data to support licensure of the vaccine candidate.
Sinopharm Group is speeding up development of a candidate vaccine for the novel coronavirus that causes COVID-19, with more milestones having been achieved by the Chinese State-owned pharmaceutical giant ahead of hoped-for mass production.
Among them, CanSino Biologics is using Sartorius' BIOSTAT bioreactor for developing its coronavirus vaccine candidate that has recently been approved to enter a Phase 2 clinical trial, the first to reach this stage worldwide.
Last month, Chinese authorities approved clinical trials for a recombinant vaccine candidate by the Academy of Military Sciences of the People's Liberation Army and Chinese biotech firm CanSino Bio.
After e-commerce success in various regions, Jollychic hits pay dirt in Middle EastEven with a bachelor's degree in computer science from Jordan's Hashemite University, Noor Hayida was turned down by 18 employers for one reason: a female candidate is not welcome.
The company has initiated efforts to develop a coronavirus vaccine candidate and broadly collaborate with others to screen a library of antiviral therapies, according to a press release.
Each interviewee scored candidate companies on nine criteria including management quality, product or service quality, innovation ability, long-term investment value, financial status, ability to attract and maintain talent, social responsibility, reasonable utilization of assets, and effectiveness of global operations.
About 391 candidate companies were under consideration and these firms were mainly top 500 Chinese companies worldwide and in China.
"I use Yinxiang Biji every day to store and classify my experimental data and materials," said Leo Zhang, a 29-year-old doctoral candidate in Beijing.
In March, Democratic presidential candidate Senator Elizabeth Warren of Massachusetts put in her campaign platform a pledge to introduce legislation targeting tech companies with annual revenue of $25 billion or more with more regulation.
"I applaud Facebook co-founder Chris Hughes for sounding the alarm on the dangers of unchecked corporate power," Democratic presidential candidate Senator Bernie Sanders of Vermont tweeted Friday.
Democratic presidential candidate Senator Kamala Harris of California called Facebook "a utility that has gone unregulated" and highlighted the issue of privacy, about which "serious regulation" should be enacted.
This is driving employers to consider the technical expertise of a candidate to be of paramount importance, above other factors such as leadership qualities or salary expectations," said Simon Lance, managing director at Hays China.
Experienced teachers evaluate the applicant's performance, which determines at which level the selected candidate would teach.
Meituan is considered a prime candidate to sell shares in the Chinese mainland as part of the government's program to give more opportunities to domestic investors.
When he was the Republican presidential candidate, Donald Trump said he would oppose the deal "because it's too much concentration of power in the hands of too few".
Announced in October 2016, the deal was quickly denounced by Donald Trump, who as a candidate and later as president has been critical of Time Warner's CNN and its coverage.
Wang Jin, a PhD candidate at the School of Political Science at the University of Haifa in Israel, said that "as a country of entrepreneurship, Israel has a large number of startups and innovative technologies, and China's manufacturing industry is well-developed, which can help transform Israeli technologies into products, that then enter the Chinese market. "
"Hiroki Imabayashi, a doctorate candidate at Waseda University and CEO of an artificial intelligence data security company, asked Ma about how to select team members that one can trust.
Seiya Ashikari, also a doctorate candidate, started a company to make insects into fish feeds.
Along with multiple ministries, the CSRC would search for candidate companies engaged in areas like industrial internet and artificial intelligence, Yan told reporters on the sidelines of the annual gathering of the top legislature on Thursday.
After only eight months as chairman, Sun will also leave the board of Leshi, and Liu Shuqing, the company's general manager, will serve as acting chairwoman before the board picks a new candidate, Leshi said in an announcement on Wednesday.
The meeting, held for the first time this year, will bring six proposals to the table, which include change of the company's registered capital, modification on the company's articles of association, providing a guarantee for holding subsidiaries, appointing Yang Qing as the supervisor of the third board of supervisors of the company, changing the accounting firm and nominating Wang Lei to be a candidate for the independent director of the third board of the company.
Jeffrey Henderson, another Qualcomm board director, was added last year as a compromise candidate.
After taking the stake in CICC, Tencent will be authorized to nominate a candidate for company director.
Typically, these are hosted by professional anchors who introduce the employer, explain the role, elaborate on the right candidate and field text queries from viewers who are then invited to fill out and submit digital application forms.
Besides, the company's first AI-discovered drug candidate, for the treatment of a rare and chronic lung disease called idiopathic pulmonary fibrosis, has finished dosing subjects for a phase-1 clinical study in China.
Efforts will be made to deliver the remainder of the quota at a faster pace, prioritizing regions with a strong ability to pay service debt and with sufficient candidate projects.
Long is a researcher with CEIBS Lujiazui Institute of International Finance and Wang is a doctoral candidate at Shanghai University of Finance and Economics.
His background made him the perfect candidate for the position, taking charge of the group's project development and management.
The writer is a senior researcher of Postal Savings Bank of China, and a postdoctoral candidate at the State Information Center.
A most recent case is an out-license agreement settled between Chinese biopharmaceutical company Harbour BioMed, or HBM, and UK company AstraZeneca earlier this month, for a novel drug candidate known as HBM7022.
According to the deal agreement, AstraZeneca will be granted an exclusive global license for the research, development, registration, manufacturing and commercialization of the drug candidate and shall be solely responsible for all costs and activities associated with its further development and commercialization.
Wang Jingsong, founder, chairman and CEO of HBM, said the drug candidate is one of the company's representative innovative bispecific antibodies generated from its self-developed antibody development platform called HBICE and has significant potential value on a global basis.
It triggers rapid and large-scale responses, such as a reliance on virtual care delivery, an increased focus on mental health and wellbeing, and a push for quicker drug and vaccine candidate discoveries.
The novel anti-fibrotic target and the drug candidate were both discovered by Insilico using an AI platform.
The company has also nominated a preclinical candidate compound for innovative cancer immunotherapy in a collaborative project with Chinese pharmaceutical giant Fosun Pharma.
The candidate compound is a potential first-in-class small molecule inhibitor, Insilico claims.
Jiang Hualiang, a pharmaceutical scientist and an academician at the Chinese Academy of Sciences, said at an industry forum in Shanghai last year that AI technology could speed up new drug discovery at various R&D stages, from discovering new drug targets and drug candidates, to candidate optimization and clinical research.
A global leader in SHP2 inhibitor development, the company has finished phase-1 clinical study of an SHP2 inhibitor drug candidate and determined recommended doses of monotherapy and combination therapy with PD-1 antibody.
For instance, Shanghai Junshi Biosciences Co Ltd, a Chinese innovation-driven biopharmaceutical company, announced in March a global phase-3 trial on the efficacy and safety of VV116, a treatment candidate for moderate to severe COVID-19.
Now it has over 550 staff in over 15 countries, with a rich pipeline that includes a phase-3 COVID-19 vaccine candidate.
Hays said that the BD position requires a candidate to possess a multifaceted skill set.
An appropriate candidate must have both pharmaceutical knowledge and good business awareness.
Pending an emergency use listing from the World Health Organization for its COVID-19 vaccine candidate, Clover is to provide up to 414 million doses of its protein-based COVID-19 vaccine candidate for procurement through COVAX, including 64 million doses available in 2021.
The Chinese startup is the second drug developer worldwide to engage in clinical development of an SHP2 inhibitor drug candidate, following Novartis.
InnoCare Pharma Ltd, also founded in 2015, announced in mid-July a license and collaboration agreement with US-based Biogen Inc－a recognized leader in neuroscience－for orelabrutinib, a drug candidate for the potential treatment of multiple sclerosis.
A candidate vaccine of China National Pharmaceutical Group (Sinopharm) was conditionally approved for use on Dec 31, a day after the company announced results of its phase 3 study showing the vaccine to be 79 percent effective in preventing COVID-19.
Sinovac Biotech Ltd's vaccine candidate is now conducting phase 3 human testing, and is expected to finish its capacity expansion project soon to increase annual production capacity to 1 billion doses.
The company's prostate cancer drug is undergoing phase-three global clinical trials as a promising candidate for a $10-billion annual market sector globally.
The company has also invested in a Shanghai-based company that owns an original drug candidate for type-2 diabetes.