n.穷困潦倒，无家可归的人
adj.穷困潦倒的

原形：down-and-out复数：down-and-outs

He's down and out after losing his job and his home.
他在失去工作和家园后陷入困境。
The once-prosperous businessman is now down and out on the streets.
这位曾经繁荣富有的商人现在流落街头。
She was forced to declare bankruptcy, leaving her feeling completely down and out.
她被迫宣布破产，这让她感到彻底绝望。
After a series of setbacks, he found himself down and out with nowhere to turn.
在一连串的挫折之后，他发现自己走投无路。
The boxer hit the canvas and didn't get up before the count of ten; he was officially down and out.
拳击手倒在拳击台上，在裁判数到十之前没能站起来；他已经正式被判出局。
The economic recession left many people down and out, struggling to make ends meet.
经济衰退让许多人陷入困境，挣扎着维持生计。
Despite his best efforts, John couldn't escape the cycle of poverty that had him down and out for years.
尽管约翰已经竭尽全力，但他仍无法摆脱多年来让他穷困潦倒的生活循环。
When his parents passed away, he felt like he'd been knocked down and out by life.
当他的父母去世时，他感觉生活给了他沉重的一击，使他陷入低谷。
Many homeless people were formerly middle-class citizens who became down and out due to unforeseen circumstances.
许多流浪者曾是中产阶级公民，但由于不可预见的情况而沦落为社会底层。
Despite being down and out, she remained determined to pick herself back up and start anew.
即便身处逆境，她依然坚定决心重新振作起来，开始新生活。